10 Diseases Caused by Evolutionary Mismatches

Many of the diseases and health problems that plague us in modern times are caused by a mismatch between genes and environment. This statement is supported by a large body of evidence (includes fossil studies, clinical trials,++). The number of mismatch diseases that affects contemporary people is staggering. Virtually every human alive today will develop […]

The Etiology, Prevention, and Treatment of the Diseases of Civilization: A Darwinian Conceptual Framework

I know that a lot of the concepts I talk about here on Darwinian-Medicine.com, such as evolutionary mismatches and biome reconstitution, may seem foreign and complicated to a lot of people. In order to make things more clear and help new readers understand what this site is all about, I’ve created a figure/infographic that explains […]

Biome Reconstitution: What Mark Zuckerberg Should be Investing In

In my previous article here at Darwinian-Medicine.com I took a critical look at Mark Zuckerberg’s plan to cure all diseases. I made the case that pumping billions of dollars into the development of new drugs and advanced medical technology is not the way to combat the chronic diseases of civilization. Health disorders such as obesity, […]

Why Mark Zuckerberg’s Mission to “Cure All Diseases” is Somewhat Misguided

The other day I was lying in bed scanning through Facebook on my phone. I was bored and didn’t feel like doing anything productive, so I ended up spending a lot more time on the site than I usually do, and I visited several pages that I rarely frequent. One of the pages I stumbled […]

The Science of Darwinian Medicine: A Talk by Robb Wolf

What is Darwinian medicine? What separates it from conventional medicine? And how can Darwinian medicine be applied in a clinical setting? If you are a long-time reader of this blog, you probably know the answer to all of these questions. However, if you are a new reader, or someone who hasn’t dug into the science […]

Are “Bad Genes” to Blame for Your Health Problems?

The Human Genome Project (HGP), an international research project aimed at mapping all of the genes that make up the human genetic make-up, held much promise. Many scientists and laypeople alike were convinced that we would finally get the answers we need to effectively treat cancer, heart disease, and many other health conditions. The disappointment […]

What Happens When Contemporary Humans Adopt a Hunter-Gatherer Lifestyle?

Up until about 12.000 years ago, all humans lived as hunter-gatherers. This was how things had been for millions of years. Today, however, very few true hunter-gatherers are left on this planet. We’ve traded in our original way of life for a modern, high-tech existence. Most people would probably say that this is a good […]

The Pitfall of Evidence-Based Nutrition & Medicine

These days, you don’t have to look far and wide to find information about nutrition, fitness, and medicine. There are millions of blog posts, news stories, books, and magazine articles covering these topics out there. Many of these are written by people – including nutritionists, doctors, scientists, and self-proclaimed fitness experts –  who use Randomized […]

Evolutionary Mismatches: 6 Videos That Explain Why We Get Sick

I talk a lot about evolutionary mismatches here on Darwinian-Medicine.com – and for good reason. Many, if not most, of the chronic ills that affect contemporary human populations are caused by a mismatch between genes and environment. By combining the evolutionary discordance/mismatch model with other key concepts of Darwinian Medicine (e.g., trade-offs), we get a […]

Inflammation: The Root Cause of Chronic Disease?

Your immune system is magnificent. It has been shaped over eons of time in response to environmental pressures. We humans no longer have to compete with other animals for food or escape large predators that lurk in the wild, but that doesn’t mean our struggle for existence is over. We still have to change in […]


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